Personalized escitalopram dosing for anxious teens
Treatments studied
Part of Mental health clinical trials.
This study tests whether a genetics-guided approach to choosing and adjusting escitalopram (an anxiety medicine) can improve safety and effectiveness for anxious teens. It also checks that participants have certain anxiety severity scores and can safely take the study medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 12 to 17 years old, and a parent/guardian can join consent and safety monitoring.
- You have anxiety that fits specific diagnoses (generalized, social, and/or separation anxiety), confirmed by a structured interview.
- Your anxiety symptom scores are high enough at two study visits (PARS) and your overall severity is high enough (CGI-S).
- No major start or changes to psychotherapy within the last 8 weeks, and any current therapy must have been stable for at least 2 months.
- You can attend follow-up visits at least from within about 90 minutes of the university and have no concerning suicide risk at screening.
- You can safely take the medication (normal exam/EKG for QTc, not pregnant, negative drug test, no escitalopram allergy, and you can swallow capsules).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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