Testing a detailed bowel pressure test for hard-to-treat constipation
Part of Digestive system clinical trials.
This study checks whether a “high-resolution manometry” test (a thin tube measuring bowel muscle pressure) helps doctors understand and manage constipation. It’s for adults with long-lasting constipation that has not improved with standard laxatives, and who meet specific safety and colon-testing criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old
- Your constipation has lasted more than 6 months
- Your bowel movement test shows slow bowel transit (more than 100 hours)
- Your colonoscopy was normal, with no concerning causes found
- Your constipation did not improve after trying at least two types of laxatives (one osmotic and one stimulant)
- You can safely have the pressure test (no major safety reasons like blockage, unsafe bleeding risk, or reasons you can’t have sedation)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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