Preventing Memory and Thinking Decline With Multidomain Program
Part of Brain & nervous system, Mental health clinical trials.
This study tests a multi-part program (not just one activity) to help slow down memory and thinking decline in older adults at higher risk. You would complete brief thinking tests and follow the study’s coaching/intervention schedule to see if it helps over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 60 and 85 years old and willing to fully join all study visits and activities
- Have a higher-than-average dementia risk score (CAIDE score of 6 or higher)
- Show signs of lower-than-expected thinking on at least one of three short tests or have ongoing memory complaints compared with before
- Able to take the study’s thinking tests and join brain-stimulation sessions (for example, no major sensory limits, severe reading issues, or inability to participate)
- Do not have significant depression or dementia already (screening depression score must be below 9; thinking level must not be too low)
- Not have major medical or brain conditions that can explain or worsen thinking problems or make the program unsafe (including certain heart, stroke, cancer history, recent fractures, and major psychiatric illness)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks for ways to lower the risk of developing dementia and improve thinking skills in people over 60. You may be eligible if you do not have dementia but have early warning signs of memory or thinking changes.
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
This trial tests whether a lifestyle program can help people with mild memory problems (subjective cognitive decline or mild cognitive impairment) who also have at least two things that increase their risk for dementia, like high blood pressure or lack of exercise. If you're 50 or older and have these memory issues and risk factors, you may be able to join.
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
This trial tests a website program designed to help older adults keep their memory and thinking skills sharp. It is for people who may have mild memory concerns and at least one health risk like high blood pressure or diabetes, but who are otherwise healthy enough to use a computer.
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Hear when a new Dementia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.