Cannabinoid treatment effects on knee pain and nerve signals
Treatments studied
Part of Bones, joints & muscles clinical trials.
This Phase 2 study tests whether a cannabinoid-related treatment changes how pain works in people with knee osteoarthritis. It uses questionnaires, MRI, and gentle nerve testing to understand if treatment helps pain and pain-related signals.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a provider-confirmed diagnosis of knee osteoarthritis
- Your knee pain has been moderate to severe for at least 6 months
- You have not used cannabis or CBD (in any form) in the past month
- You can read and speak English for consent and questionnaires
- You can safely do MRI and lie still on your back for 1–1.5 hours
- You’re willing to pause certain pain meds and substances before testing (details below)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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