Earlier ileostomy closure after rectal cancer surgery
Part of Cancer, Digestive system clinical trials.
This study looks at whether closing a temporary ileostomy sooner is safe after rectal cancer surgery, when imaging shows no leak. It may help people avoid living with the stoma for longer, but only if specific safety checks are passed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (18 years or older).
- You had rectal cancer surgery (restorative proctectomy) that created a temporary diverting loop ileostomy.
- On post-op days 7 to 9, a CT scan leak test using rectal-administered water-soluble contrast showed no leak.
- You have not had immune-suppressing medicines in the 6 weeks before your surgery (or around that time).
- You had no major complications after surgery (serious complication grade III or higher), and you don’t have too many major health problems (Charlson Comorbidity Index over 6).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a temporary stoma (a bag on the belly) can be safely avoided in some people having rectal cancer surgery. The goal is to see if it's okay to skip the stoma in those with a low risk of complications.
This trial tests whether using a medication called somatostatin plus a clear liquid diet can safely prevent serious complications after surgery to remove rectal cancer, without needing a temporary opening in the abdomen (stoma). You'll be randomly assigned to receive either somatostatin with diet changes or a stoma, depending on your individual risk factors.
This trial compares a virtual ileostomy (a system that monitors leaks without creating a temporary opening) to a traditional diverting ileostomy (a temporary bag) in people having rectal cancer surgery. The goal is to see if the virtual method is safer and avoids a second surgery.
This trial looks at why some people who had a temporary stoma (a bag for waste) after rectal cancer surgery never get it reversed. It collects information from medical records to find patterns that might explain this.
This study tests whether a simple daily stimulation technique applied before ileostomy reversal surgery can improve your bowel health and reduce complications. Researchers will compare your bowel bacteria and tissue health before and after the procedure.
This trial tests whether taking probiotics (good bacteria) from your own body can help prevent digestive problems after your ileostomy is reversed. It is for people who had rectal cancer surgery with a temporary ileostomy and are planning to have it closed within 3 to 6 months.
Hear when a new Ileostomy - Stoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.