Somatostatin and Diet vs. Stoma After Rectal Cancer Surgery
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests whether using a medication called somatostatin plus a clear liquid diet can safely prevent serious complications after surgery to remove rectal cancer, without needing a temporary opening in the abdomen (stoma). You'll be randomly assigned to receive either somatostatin with diet changes or a stoma, depending on your individual risk factors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–75 years old and have stage I–III rectal cancer scheduled for surgery
- Your tumor is located within 8 cm of the dentate line (the boundary between different types of tissue in your rectum), or within 10 cm of your anal opening
- You have at least two risk factors for anastomotic leakage (a serious complication where the surgical connection leaks), as assessed by the study team
- Your general health (American Society of Anesthesiologists score) is grade 3 or better, and your BMI is below 30
- You have not received chemotherapy within 2 weeks or radiation within 8 weeks before surgery
- You do not have inflammatory bowel disease, metastatic cancer, or allergies to somatostatin
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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