Clin2
NCT05059626Possibly a fitEnrolling by invitation

Test simvastatin and Duavee for endometriosis symptoms

Endometriosis

Treatments studied

Part of Women’s health & pregnancy clinical trials.

This trial studies whether simvastatin and Duavee can improve endometriosis-related symptoms linked to small blood-vessel problems. You may be eligible if you’re a woman aged 18–45 with confirmed endometriosis and meet safety requirements.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
28 people
Ages
18 years to 45 years
Study type
Interventional

Who can take part

  • You are a woman age 18 to 45
  • You have endometriosis confirmed by a past laparoscopy (done by your doctor within the last 10 years, and you reported it to the study)
  • You are not pregnant and are not breastfeeding
  • You do not use nicotine-containing products (like smoking or chewing tobacco)
  • You do not have diabetes (HbA1c 6.5% or higher)
  • Your blood pressure is 140/90 or lower and your liver tests are normal

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03746535Recruiting· Early Phase 1
Study heart disease risk in women with endometriosis

This early study looks at how endometriosis may affect heart and blood-vessel risk in women aged 18 to 45. It may help doctors understand risks better and plan safer prevention and monitoring for people with endometriosis.

New Haven, Connecticut
NCT05069740Recruiting· Early Phase 1
Study inflammation and blood vessel changes in endometriosis

This early study looks at how inflammation may affect small blood vessels in people with endometriosis. It may help researchers understand what’s driving symptoms like pain and what could be targeted in the future.

University Park, Pennsylvania
NCT07100782Recruiting· Phase 3
Estrogen & pain trial for endometriosis pelvic pain

This study tests whether a drug called relugolix CT can reduce pelvic pain from endometriosis. You'll have brain scans and pain tests to measure how your body processes pain. It might help if other treatments haven't worked well.

Ann Arbor, Michigan
NCT07318688Recruiting· Phase 3
Testing HMI-115 for endometriosis pain

This trial tests an experimental drug called HMI-115 to see if it reduces pain from endometriosis. If you have moderate to severe period pain and non-period pain, and you have a surgical diagnosis, you may be able to join.

Beijing, Beijing Municipality
NCT07270393Not yet recruiting
Mediterranean diet for endometriosis quality of life

This study tests whether following a Mediterranean diet (rich in fruits, vegetables, and healthy fats) can improve your quality of life if you have endometriosis. You'll receive dietary guidance and be followed for several months.

Donostia / San Sebastian, Gipuzkoa
NCT06952296Not yet recruiting
Dydrogesterone for endometriosis-related pain

This trial tests a hormone medicine called dydrogesterone (Duphaston) to see if it eases pain caused by endometriosis. It is for women with regular periods and a confirmed endometriosis diagnosis who are not using other hormone treatments.

Hear when a new Endometriosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.