Clin2
NCT05074290Possibly a fitRecruiting

Testing safety and drug levels of a breast cancer drug plus taxane

Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This early-phase study tests how epidiferphane works in the body and whether it is safe when combined with standard chemotherapy “taxanes” (paclitaxel or docetaxel) for breast cancer. If you qualify, you may be starting a new taxane treatment plan at the study site, and you would be followed closely for side effects and drug levels.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
74 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You’re 18 years or older
  • You have breast cancer (or, for the first part of the study, you’re starting chemotherapy for it or have metastatic breast cancer)
  • You are about to start a new taxane regimen at UF Health (paclitaxel or docetaxel, weekly or every 3 weeks depending on the dose schedule)
  • Your cancer care must continue at UF Health for at least the next 3 months
  • You can take part safely: no major digestive blockage, not pregnant or breastfeeding, and you can follow the study rules
  • You must not be on other experimental (investigational) medicines

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06199895Recruiting· Phase 2
Study of paclitaxel for patients with taxane-resistant solid tumors

This trial tests paclitaxel given as tiny micelle particles for people whose cancer (pancreatic, bile duct, lung, stomach, esophagus, or breast) stopped responding to taxane chemotherapy or did not shrink. The goal is to see if this treatment can help when standard taxanes no longer work.

Wuhan, Hubei
NCT06765590Recruiting
Paclitaxel (albumin-bound) bioequivalence study in breast cancer

This study tests whether a new version of paclitaxel (albumin-bound) works the same as the approved version in people with breast cancer. It's for patients whose cancer has spread or returned after other treatments, or those for whom this drug is recommended by treatment guidelines.

Luoyang, Henan
NCT04136782Recruiting· Phase 4
Tests two chemo drug combinations for triple-negative breast cancer

This Phase 4 trial compares two chemotherapy combinations to treat stage II–III triple-negative breast cancer. It looks for which regimen works better and is tolerated in people with measurable tumors and good overall health.

Harbin, Heilongjiang
NCT05728268Recruiting· Phase 2
Test dose-dense chemo before surgery for high-growth hormone-positive breast cancer

This Phase 2 study tests a faster, more frequent chemotherapy schedule given before surgery (neoadjuvant therapy) for certain breast cancers that grow quickly. It may help shrink the tumor before the operation and improve treatment response in people who fit the tumor and health criteria.

Shantou, Guangdong
NCT07441486Not yet recruiting· Phase 2
Combination treatment for advanced breast cancer

This study tests a combination of two medications, entinostat and an oral form of paclitaxel, for people with advanced breast cancer that is hormone receptor positive and HER2-negative. If you've already tried several treatments, this might be a new option to help slow the cancer's growth.

NCT04400695Recruiting· Phase 3
Targeted drug for breast cancer with low HER2 levels

This trial tests a new drug that targets breast cancer cells with low levels of the HER2 protein. It may offer a new treatment option for patients whose cancer has spread and not responded well to previous therapies.

Beijing, Beijing Municipality

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.