Study of sentinel lymph nodes in vulvar cancer
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This Phase 2 study looks at how vulvar squamous cell cancer (SCC) spreads to the sentinel lymph node, and how findings may guide treatment. It focuses on specific early-stage tumor features and requires that cancer is found in the sentinel lymph node.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have vulvar squamous cell carcinoma confirmed by biopsy (not another type of vulvar cancer).
- Your vulvar tumor is small: T1 stage, less than 4 cm, and not growing into the urethra, vagina, or anus.
- The tumor has invaded more than 1 mm deep, and it is only one (unifocal) tumor.
- Scans (CT/MRI/ultrasound) should not show suspicious groin lymph nodes larger than 1.5 cm, and your sentinel lymph node must be found to have spread (including certain cases with small metastasis).
- You must be able to consent, follow study steps, and attend follow-up; age 18+; and expected survival of at least 12 weeks.
- Blood tests and general health must meet targets (enough white blood cells, platelets, good kidney and liver function), and heart conditions should be stable; you should not be pregnant or trying to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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