Primary care program for mood and thinking in early Alzheimer’s
Part of Mental health, Pain clinical trials.
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 60 or older
- Have mild cognitive problems or early Alzheimer’s (early stage) and at least mild thinking issues (MoCA score between 16 and 25)
- Have at least mild depression symptoms (MADRS score 5 or higher)
- Be able to consent, and have an available study partner (caregiver/family member/significant other) who will join the study
- If you take certain medications (antidepressants, donepezil/rivastigmine/other cholinesterase inhibitors, or memantine), be either completely off them or on a stable dose for at least 12 weeks
- Have chronic pain most days for at least 3 months with an average pain level of 4 or higher
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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