Kidney transplant test using machine perfusion outside the body
Part of Kidney & urinary clinical trials.
This study tests a special way to keep and treat a donated kidney using a machine before it’s transplanted. The goal is to improve transplant outcomes for certain people on the kidney transplant waiting list.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You are on dialysis and waiting for a kidney transplant at this center
- This would be your first or second kidney transplant
- You plan to receive a kidney from a specific type of older donor (70+) or a donation after cardiac death under certain rules
- You can follow the study plan for about 1 year and give signed consent (or a guardian can sign if needed)
- Your medical team says you meet the usual eligibility rules for a kidney transplant at this site
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a machine method that keeps a donated kidney working “outside the body” so it may be better repaired before transplant. It is designed for certain first/second kidney transplants using specific donor types and storage methods.
This study checks if pumping a special fluid through donor kidneys (machine perfusion) helps predict how well the kidney will work after transplant. It's for people getting a kidney from an older donor or one with some health issues.
This study compares two ways of preserving kidneys from older or less healthy donors before transplant – one using a machine that pumps fluid through the kidney, and one without. It may help improve how well these kidneys work after transplant.
This trial tests if a machine that pumps warm oxygenated blood through livers that were considered unsuitable for transplant can help doctors decide if they are actually safe to transplant. If so, it could increase the number of available livers for people waiting for a first liver transplant.
This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).
This trial compares two ways of preserving kidneys from donors after cardiac death before transplanting them into recipients. One method uses a machine that pumps oxygenated fluid through the kidney (called NRP), and the other uses the same method plus an additional oxygen treatment (HMPO2). The goal is to see if the extra treatment improves kidney function after transplant.
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