Clin2
NCT05205317Possibly a fitRecruiting

VR alone or VR plus metformin for C-section scar healing

Defect

Part of Women’s health & pregnancy clinical trials.

This study compares two treatments to help improve a C-section scar defect (an issue seen on the uterus scar). Some participants may receive virtual reality (VR) therapy plus metformin, while others receive VR alone, and the researchers will look at symptoms and scar healing.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years to 40 years
Study type
Interventional

Who can take part

  • Your age is between 18 and 39 years old.
  • You have a confirmed diagnosis of a C-section scar defect (CSD).
  • Your main symptoms include abnormal uterine bleeding, with menstrual bleeding lasting more than 10 days.
  • Your C-section scar area is thin: the remaining muscle layer is less than 3 mm.
  • Your blood sugar and insulin are in the normal range.
  • You do NOT have uterine fibroids, endometriosis, or adenomyosis, and you do NOT have any cancer.
  • You are not pregnant and you can follow the study plan and sign consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05206682Recruiting
Treating C-section scar defect with hormones versus surgery alone

This trial compares two treatments for a pregnancy-related problem in the uterus: vaginal repair alone versus vaginal repair plus leuprorelin (a hormone medicine). It aims to improve symptoms like long or heavy bleeding when a C-section scar defect is also linked with adenomyosis.

Shanghai, Shanghai Municipality
NCT07272967Not yet recruiting· Phase 4
Metformin for preventing scarring after spinal cord injury

This trial tests whether the drug metformin can reduce scarring (gliosis) in the spinal cord after a recent thoraco-lumbar injury. If you've had a spinal cord injury in the past 24 hours and meet the criteria, you may be able to join.

Shibīn al Kawm, Menoufia
NCT06917014Not yet recruiting
Hysteroscopic surgery for cesarean scar defects

This trial tests a special hysteroscopic surgery to improve symptoms like long periods caused by a cesarean scar defect. It may help women who haven't gotten better with birth control pills or who strongly prefer surgery.

NCT04581447Recruiting· Phase 3
Metformin to help prevent diabetes returning after weight surgery

This Phase 3 study tests whether adding metformin after gastric bypass or sleeve surgery can help you stay free of diabetes for longer. It compares metformin plus standard care versus standard care alone.

Amiens
NCT05643703Not yet recruiting
Treating a weak C-section scar causing long bleeding

This study tests a repair approach done through the vagina to fix a specific problem in the uterine scar from a prior C-section. It’s meant for people who have ongoing, long menstrual bleeding after C-section when medicines haven’t helped and other causes have been ruled out.

NCT06064669Recruiting
Metformin for healthy live birth in women with prediabetes

This study tests if metformin, a drug that helps control blood sugar, can improve the chance of a healthy live birth in women with prediabetes who are doing in vitro fertilization (IVF). It aims to see if treating prediabetes before and during early pregnancy leads to better outcomes.

Jinan, Shandong

Hear when a new Defect trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.