Treating C-section scar defect with hormones versus surgery alone
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This trial compares two treatments for a pregnancy-related problem in the uterus: vaginal repair alone versus vaginal repair plus leuprorelin (a hormone medicine). It aims to improve symptoms like long or heavy bleeding when a C-section scar defect is also linked with adenomyosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a clear diagnosis of a C-section scar defect plus adenomyosis
- Your main symptom includes abnormal bleeding, with periods lasting over 10 days
- Your remaining uterine muscle layer at the scar is thinner than 3 mm
- Your blood sugar and insulin are in the normal range
- You do not have major organ illnesses or uncontrolled conditions (like uncontrolled diabetes)
- Your fibroids (if any) are 5 cm or smaller
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a repair approach done through the vagina to fix a specific problem in the uterine scar from a prior C-section. It’s meant for people who have ongoing, long menstrual bleeding after C-section when medicines haven’t helped and other causes have been ruled out.
This trial compares surgical repair of a large C-section scar defect to expectant management (watchful waiting) for women who have been unable to get pregnant for at least 12 months. The goal is to see which approach helps improve fertility.
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