Clin2
NCT05270213Possibly a fitRecruiting

RBS2418 for advanced cancers after standard treatments

Advanced Cancer

Treatments studied

Part of Cancer clinical trials.

This early-phase study tests RBS2418 in people with advanced, metastatic solid tumors that have not responded to standard treatment. It aims to see if the drug can shrink tumors or help control disease, and to learn what doses are safest.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
164 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older and willing to sign consent for the study (and optional future research).
  • You must have an advanced, unresectable, recurrent, or metastatic solid tumor confirmed by pathology (tissue/cell test).
  • Your cancer must have been treated with standard care already, or standard options must not be available, and you should have no other standard option with meaningful benefit.
  • You must be expected to live at least 3 months and have measurable disease on scans.
  • You must be able to provide tumor tissue for testing before treatment and again on treatment (unless your doctor says biopsy is not safe).
  • You must not be pregnant or breastfeeding, and you must use highly effective birth control (and agree not to father a child) for the required time window.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06824064Recruiting· Phase 2
RBS2418 for advanced metastatic colorectal cancer

This trial tests a new drug called RBS2418 for people with advanced colorectal cancer that has spread and is getting worse, even after other treatments have stopped working. The goal is to see if RBS2418 can help control the cancer.

Newark, Delaware
NCT05487170Recruiting· Phase 1/Phase 2
Early trial of RNK05047 for advanced cancers

This Phase 1/2 study tests an experimental medicine (RNK05047) in people with advanced solid tumors or diffuse large B‑cell lymphoma whose standard treatments haven’t worked or can’t be tolerated. It may help shrink tumors and improve control of the disease, but early-phase trials also focus on safety and dosing.

Atlanta, Georgia
NCT04928612Recruiting· Phase 1
CBP-1018 for advanced cancers that no standard treatment helped

This early-phase study tests CBP-1018 in people with advanced solid tumors, such as prostate, kidney, or certain lung cancers. It aims to see how the drug works and whether it’s safe enough to continue studying.

Guangzhou, Guangdong
NCT06598735Recruiting· Phase 1
Study of HRS-4508 for advanced solid tumors

This trial tests a new drug called HRS-4508 for people with advanced or metastatic solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe, how the body processes it, and if it helps shrink tumors.

Beijing, Beijing Municipality
NCT07744152Not yet recruiting· Phase 1
Testing a new drug for advanced solid tumours

This study tests a new drug called BI 3822971 for people with advanced cancer that has not responded to standard treatments. The goal is to find the best dose that is safe and well-tolerated.

Leuven
NCT07189949Recruiting· Phase 1
Study of HRS-2329 for advanced solid tumors with RAS changes

This trial tests a new drug, HRS-2329, for people with advanced solid tumors that have a RAS mutation or amplification and haven't responded to standard treatments. It aims to see if the drug can help shrink or control the tumors.

Tianjin, Tianjin Municipality

Hear when a new Advanced Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.