Clin2
NCT05300945Possibly a fitNot yet recruiting

HIPEC after stomach cancer surgery for advanced gastric cancer

Gastric CancerPeritoneal Metastases

Part of Cancer, Digestive system clinical trials.

This trial tests a treatment called HIPEC done during/around surgery after chemotherapy for advanced stomach (gastric) cancer. It may help patients live longer or have fewer cancer-related problems after the operation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
200 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have stomach cancer that was confirmed under a microscope as adenocarcinoma
  • Your cancer is advanced: it has reached nearby lymph nodes (no distant spread), and is stage T3–T4
  • Your cancer area does not involve the esophagus more than 3 cm
  • You are well enough for treatment, with an ECOG activity score of 0 or 1
  • You have NOT had chemotherapy or radiation for any cancer before
  • You have NOT had stomach-cancer surgery before (except minor endoscopic removals like EMR/ESD)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06525714Not yet recruiting· Early Phase 1
HIPEC after stomach cancer surgery to improve survival

This trial tests if adding heated chemotherapy (HIPEC) right after stomach cancer surgery can help people with locally advanced gastric cancer live longer. It's for patients whose cancer has not spread to other parts of the body and who are fit enough for major surgery.

NCT04107077Recruiting· Phase 2
HIPEC surgery plus chemotherapy for advanced stomach cancer

This study tests whether a specialized surgery called HIPEC (heat-treated chemotherapy placed in the belly) can improve outcomes for people with advanced stomach cancer that has reached the lining of the abdomen. It’s given after you’ve already had standard chemotherapy, aiming to better control disease in the belly.

Chicago, Illinois
NCT04597294Recruiting· Phase 3
Preventive pre-op HIPEC for advanced stomach cancer

This Phase 3 trial studies whether adding a heated chemotherapy procedure during surgery (HIPEC) before the main cancer treatment can lower the chance that stomach cancer returns in the belly. It is for people with advanced stomach cancer who are at higher risk of cancer coming back in the peritoneum (the lining of the abdomen).

Krakow, Lesser Poland Voivodship
NCT05871099Recruiting· Phase 3
Laparoscopic stomach surgery with added heated fluid chemotherapy

This trial compares standard laparoscopic surgery for stomach cancer versus the same surgery plus HIPEC, which is heated chemotherapy placed in the abdomen during the operation. It aims to see if adding the heated chemotherapy improves outcomes for people with higher-stage stomach cancer.

Qingdao, Shandong
NCT05095467Not yet recruiting· Phase 2
HIPEC-AS for stomach cancer that has spread to the belly lining

This Phase 2 study tests a treatment called HIPEC-AS for stomach or food-pipe-junction cancer that has spread only to the peritoneum (the belly lining). It aims to see whether adding HIPEC-AS can improve cancer control for people who have not had prior cancer medicines.

NCT05648487Not yet recruiting· Phase 2
Treating stomach cancer in the belly lining with added immunotherapy

This Phase 2 trial studies a combination treatment for stomach (or stomach-to-esophagus) cancer that has spread to the belly lining. It tests whether adding the immunotherapy drug sintilimab to a procedure called HIPEC can improve outcomes for people who have not had prior treatment.

Hear when a new Gastric Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.