Keep the same treatment after limited metastatic growth
Part of Cancer clinical trials.
This study tests whether continuing your current systemic (whole-body) therapy is safe and helpful when only 1–2 metastatic spots start growing. It also checks whether adding local treatment (such as radiation or ablation) to those spots can better control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed invasive breast cancer that has spread (metastatic).
- Your cancer is growing in only 1–2 places (“oligoprogression”) and it’s limited to one organ, or a nearby primary/lymph-node area.
- You have been on your current whole-body treatment for at least 6 months, with stable disease or partial/complete response for at least 6 months.
- Scans show the limited growth within about 70 days before the local treatment, and you can have a follow-up FDG-PET-CT scan 5–7 weeks later.
- The new growing spot(s) can be treated locally (surgery, radiation, or radiofrequency ablation) with the goal of destroying them.
- You’re age 18 or older and can do usual activities (WHO performance status 0–1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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