Letrozole or mifepristone before medication abortion
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This study tests whether taking letrozole or mifepristone before medication helps the medical abortion work better for pregnancies up to 10 weeks. You may be asked to try another method (repeat medicine or a procedure) if the first treatment does not fully work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years old or older
- You are choosing a medical (pill-based) termination of pregnancy
- Your pregnancy is up to 10 weeks along (confirmed by an early ultrasound)
- The pregnancy is a single baby (not twins or more)
- You understand and agree to have a procedure or repeat pills if needed
- You can sign written informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two different medicines (Mifepristone vs Misoprostol) to see which works better for ending a pregnancy in the second trimester (12–16 weeks). It is for people who are pregnant with one baby and have no major health issues that could affect safety.
This study compares two medication combinations to see which is more effective for ending a pregnancy in the second trimester (14-20 weeks). It may help women who need this procedure have a safer and more successful experience.
This study compares two ways of taking the abortion pill misoprostol to find out which is more effective and acceptable for people ending an early pregnancy (up to 11 weeks). You would receive standard care and help doctors learn how to improve early abortion options.
This study tests whether taking letrozole (a hormone-modifying drug) before misoprostol (a medication that helps empty the uterus) can shorten the time needed to complete a missed miscarriage. It may help make the process faster and more effective.
This Phase 2 study tests whether mifepristone, taken by mouth, can help start labor when the cervix is not ready yet. It may help avoid needing other methods of induction, but it will only be offered if it’s safe for you and your baby.
This trial tests whether adding letrozole (a hormone pill) to misoprostol (a medicine to complete a miscarriage) works better than misoprostol alone for ending a missed miscarriage in early pregnancy. It aims to make the process safer and possibly faster.
Hear when a new Abortion in First Trimester trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.