Comparing two medications for second-trimester abortion
This study compares two medications—letrozole plus misoprostol versus misoprostol alone—to see which is more effective for ending a pregnancy in the second trimester (14–20 weeks) after the fetus has stopped developing. The goal is to find a safer, more comfortable method for women who need this procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman aged 18 to 45 years.
- You must be between 14 and 20 weeks pregnant, confirmed by ultrasound.
- The pregnancy must have stopped growing (missed abortion or fetal demise).
- Your cervix must be closed and you must not have any tissue protruding from the cervix.
- You must not have heart, kidney, bleeding disorders, or allergies to the study drugs.
- Your BMI must be 35 or lower.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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