Clin2
NCT05373758Possibly a fitRecruiting

Help for people whose HIV treatment is not working

HIV InfectionsAIDSVirologic Failure

Part of Immune system & allergy, Infections clinical trials.

This trial tests different ways to manage “virologic failure,” meaning HIV viral load stays high while taking TLD (a common HIV medicine combination). It may help people better control the virus and improve treatment results, especially in parts of sub-Saharan Africa.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
648 people
Ages
15 years and older
Study type
Interventional

Who can take part

  • Be age 15 or older
  • Be enrolled in HIV care at a study clinic
  • While on TLD, have had two viral load tests showing HIV levels above 1,000 copies/mL
  • Have been taking TLD for at least 12 months
  • Live within 100 kilometers of the study clinic
  • You should be able to stay with the same clinic for the next 48 weeks

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT00187512Recruiting
Study of how HIV treatment changes outcomes over time

This is an observational study (not a new drug) that tracks how living with HIV can change over time in different treatment situations. It may help researchers understand long-term effects of the modern “protease inhibitor era” and improve future care.

San Francisco, California
NCT06441123Recruiting
A trial of a new HIV latency-reversing drug

This trial tests a new type of medicine that aims to wake up HIV hiding in your body's cells by targeting a viral protein called Tat. The goal is to help find a way to clear the virus completely.

Montpellier
NCT06762054Recruiting
Better management for dolutegravir-resistant HIV

This trial tests better ways to manage HIV when the virus becomes resistant to dolutegravir (DTG), a key medicine. It is for people with high viral load despite being on DTG for at least six months.

Kisumu
NCT06842706Not yet recruiting
HIV drug resistance study for people with viral failure

This study looks for drug-resistant HIV strains in people whose virus is not fully controlled by their current treatment. It aims to help doctors understand why the virus is still detectable.

NCT06485154Recruiting· Phase 4
Finding the best HIV treatment after PrEP shot failure

This trial is for people who got exposed to HIV despite taking the long-acting PrEP shot (cabotegravir). It tests different pill-based HIV treatment plans to find the best option for them.

Johannesburg, Gauteng
NCT07792096Not yet recruiting· Phase 3
Testing new HIV treatments for children and teens in Africa

This trial compares new HIV medicines to help children and teens who have HIV and are either starting treatment or whose current treatment isn't working. The goal is to find better ways to control the virus and keep kids healthy.

Hear when a new HIV Infections trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.