Clin2
NCT05453682Possibly a fitRecruiting

Radiation plus chemotherapy to preserve the bladder

Bladder Cancer

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests whether a shorter, more focused radiation plan given at the same time as chemotherapy can control muscle-invasive bladder cancer while keeping the bladder. You may be offered bladder-preserving treatment if your cancer stage and health conditions fit the study rules.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
53 people
Ages
20 years and older
Study type
Interventional

Who can take part

  • You have bladder cancer confirmed under a microscope
  • Your tumor has reached the muscle layer or deeper (T2 or higher) after surgery
  • Your pelvic lymph nodes look clear on pelvic CT or MRI (no spread there)
  • You want to keep your bladder (bladder-conserving treatment)
  • You are age 20 or older and can do usual daily activities (ECOG 0–1)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07043543Not yet recruiting
Adaptive radiation therapy for bladder cancer

This trial tests a new type of radiation therapy that adjusts to your body's changes during treatment. It aims to reduce side effects and improve accuracy for people with bladder cancer.

Dijon, Côte d'or
NCT06586255Recruiting· Phase 1
Immunotherapy and radiation after bladder cancer surgery

This trial tests whether adding radiation therapy to immunotherapy after bladder removal surgery can help prevent cancer from coming back. It's for people with advanced bladder cancer who have already started immunotherapy.

Philadelphia, Pennsylvania
NCT06310369Not yet recruiting· Phase 2
Radiation therapy for bladder cancer that has not responded to BCG

This trial tests whether radiation therapy (high-energy beams to kill cancer cells) can be a good treatment for bladder cancer that hasn't gone away after BCG therapy, offering an alternative to surgery to remove the bladder. It aims to see if this approach can control the cancer while possibly preserving your bladder.

NCT06470282Recruiting· Phase 1/Phase 2
Drug combo plus radiation for muscle-invasive bladder cancer

This trial tests a combination of two drugs (enfortumab vedotin and pembrolizumab) plus radiation therapy for people with bladder cancer that has grown into the muscle layer. The goal is to see if this treatment can kill the cancer while avoiding the need for bladder removal surgery.

San Francisco, California
NCT07097142Recruiting· Phase 3
Shorter radiation for bladder cancer with chemo

This trial tests if a shorter course of radiation therapy works as well as the usual longer course for people with bladder cancer who are also receiving standard chemotherapy. The goal is to see if shorter treatment can reduce side effects while still being effective.

Fort Smith, Arkansas
NCT07865611Not yet recruiting· Phase 2
Bladder preservation with targeted drugs and radiation for HER2-positive bladder cancer

This trial tests a combination of two drugs (trastuzumab rezetecan and adebrelimab) plus radiation to the bladder, aiming to preserve the bladder instead of removing it. It's for people with muscle-invasive bladder cancer that shows a specific marker called HER2.

Wuhan, Hubei

Hear when a new Bladder Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.