Total pancreas surgery with insulin graft for chronic pancreatitis pain
Part of Digestive system clinical trials.
This trial tests a two-part surgery: removing the pancreas and then putting the patient’s own insulin-making cells back into the body to help control long-term pancreatitis pain. It is aimed at adults with severe, long-lasting pain who have not improved with medicines or procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and able to consent (or have a legal representative consent for you)
- You must have enough insulin-making ability (not having diabetes, or having a positive C-peptide test)
- Your pancreatitis pain must be long-term (over 6 months), with test results that confirm chronic pancreatitis and/or a genetic history, and you must have failed maximal medical/endoscopic treatment
- You must have enough overall health for surgery (ECOG 0 to 1) and expect to live more than 2 years
- You must be willing to avoid alcohol and tobacco for 6 months before enrollment, and you must not be pregnant
- You must not have had prior islet cell transplantation, significant liver disease, or certain high-risk pancreatic tumors
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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