Clin2
NCT05466851Possibly a fitRecruiting

Study testing anxiety and depression biology and therapy markers

DepressionAnxiety DisordersStress Related Disorder

Part of Mental health clinical trials.

This study looks at “biopsychosocial markers” (biological, psychological, and social signs) in people with major depression and/or anxiety. It aims to understand what changes with treatment and how those changes connect to symptoms like anxiety and depression.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years to 65 years
Study type
Observational

Who can take part

  • Be between 18 and 65 years old.
  • Have enough understanding to consent and complete required study tests.
  • Currently meet diagnostic criteria for major depression (single episode or repeated episodes).
  • Also have anxiety and/or related conditions, such as panic disorder, social anxiety, generalized anxiety, OCD, PTSD, or ADHD—if the study clinician agrees.
  • Be willing to receive study treatment, including both medication management and psychotherapy.
  • Not have major serious or unstable health problems in key organs (like heart, lungs, liver, kidneys, or immune system).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07340281Recruiting
Exercise and biomarkers for anxiety

This study looks at how exercise affects certain markers in the body in people with anxiety disorders. You may be able to join if you are currently sedentary and have generalized anxiety, social anxiety, or panic disorder.

New York, New York
NCT06004115Recruiting· Phase 4
Brain scanning study for depression and anxiety

This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.

Tulsa, Oklahoma
NCT00024635Recruiting
Understanding Mood and Anxiety Disorders Study

This research study evaluates people with mood disorders (like depression or bipolar disorder), anxiety disorders, or people without these conditions to better understand how these conditions develop and affect the brain. Researchers will ask questions and may do other assessments to learn more.

Bethesda, Maryland
NCT00018057Recruiting· Phase 2
Brain study of pediatric anxiety disorders

This study looks at how the brain works in children and adults with anxiety disorders. It uses brain scans (fMRI) and other safe tests to understand anxiety better.

Bethesda, Maryland
NCT04713722Recruiting
Study of early stress and depression using brain imaging

This study looks at how early life stress may be linked to depression, using brain scans. You’ll be asked about your history and asked to do brain imaging to help researchers understand these brain and mood changes.

Belmont, Massachusetts
NCT05547711Not yet recruiting
Predicting depression course with physical and psychological markers

This study looks at physical and psychological signs that might help predict how depression develops over time. It's a naturalistic study, meaning researchers observe what happens in usual outpatient care without changing it, to see if certain markers can forecast the course of depression.

Munich, Bavaria

Hear when a new Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.