Study drug for hard-to-treat bladder infection in women
Part of Infections, Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 trial tests LBP-EC01 to treat a bladder infection (UTI) caused by drug-resistant E. coli. It may help by targeting the specific bacteria that make UTIs harder to cure with common antibiotics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’ve had a UTI in the last 12 months, and your current bladder infection is caused by drug-resistant E. coli
- Your symptoms started recently (you’re not dealing with symptoms for more than 5 days)
- You can provide a clean-catch urine sample for testing and may need stool and blood samples
- You have UTI signs and symptoms like burning, frequent urination, urgent need to go, or lower belly (suprapubic) pain—along with lab evidence of inflammation
- You will avoid taking antibiotics or UTI medicines for the first 10 days of the study (unless the study team tells you otherwise)
- If you can get pregnant, you’ll use very reliable birth control during the study and for 2 weeks after the last dose
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 trial tests whether switching from short-term IV antibiotics to an oral antibiotic combo is safe and effective for ESBL urine infections. It may help you avoid staying on IV antibiotics as long, if your bacteria are the right match.
This trial tests a new vaccine to prevent urinary tract infections (UTIs). It first checks safety and immune response in healthy adults, then in women with recent E. coli UTIs. The goal is to see if the vaccine can reduce future infections.
This study tests a new urine test (the UF-5000) to see if it can help doctors decide who really needs antibiotics for a bladder infection. The goal is to avoid giving antibiotics when they are not needed.
This study looks at urine infections caused by certain resistant bacteria. If you had a UTI treated by your family doctor between June and December 2024, your doctor may help us learn more about these infections and how to treat them better.
This trial tests two approaches to prevent repeat bladder infections in postmenopausal women: a daily antibiotic pill or a vaginal tablet containing healthy bacteria and estrogen. The goal is to see which method works better over 6 months.
This trial studies different ways to prevent repeated bladder (urinary tract) infections in women. It may help people who keep getting these infections by testing safer or more effective prevention strategies.
Hear when a new Urinary Tract Infections trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.