Clin2
NCT05515770Possibly a fitRecruiting

Injectable PrEP shot for HIV prevention in higher-risk adults

HIV Infections

Treatments studied

Part of Immune system & allergy, Infections clinical trials.

This Phase 3 study tests whether an injectable HIV prevention medicine (cabotegravir) given before exposure can help prevent HIV in people at higher risk. You may join if you are HIV-negative and meet specific sexual health, medication, and health-testing requirements.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
1,200 people
Ages
18 years to 30 years
Study type
Interventional

Who can take part

  • Be assigned male at birth (cisgender men, non-binary people assigned male, or transgender women and men) and be 18–30 years old
  • Have had anal sex with a partner assigned male at birth within the last 6 months
  • Be looking for PrEP (HIV prevention) and have not used cabotegravir LA or TDF/FTC PrEP before
  • Have negative HIV testing at enrollment (both rapid test and, if using injectable cabotegravir, an undetectable HIV RNA test)
  • Do not have significant liver problems and avoid certain medicines that can lower cabotegravir levels

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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