Finding the best lisinopril dose to prevent urine side effects
Treatments studied
Part of Cancer, Injuries & trauma, Kidney & urinary clinical trials.
This early study tests which dose of lisinopril works best to help prevent urinary toxicity (urine/burning/urinary side effects) after radiation treatment for prostate cancer. If it’s effective for you, it could make radiation easier to tolerate.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed prostate cancer of the adenocarcinoma type and are planning radiation to cure it (possibly with hormone therapy).
- Your cancer stage is M0 based on usual scans (no spread to distant sites).
- You can read English and have the physical and mental ability to complete study visits and follow-up.
- You are age 18 to under 70, and your general activity level is fairly good (ECOG 0 to 2).
- Your kidneys are working well enough (creatinine clearance above 30 mL/min) and your blood counts and liver tests meet lab thresholds.
- Your starting blood pressure is above 130 (systolic).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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