Clin2
NCT05558007Possibly a fitRecruiting

Topical treatment trial after prostate surgery in men

Erectile Dysfunction Following Radical ProstatectomyErectile DysfunctionProstate CancerRadical Prostatectomy

Treatments studied

Part of Cancer, Kidney & urinary, Mental health clinical trials.

This Phase 2 study tests how safe and effective a topical medicine (BZ371A) is for men after prostate surgery, with the goal of improving sexual recovery and monitoring side effects. You may be able to join if you meet specific timing, health, and medication criteria after radical prostatectomy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
72 people
Ages
40 years to 65 years
Study type
Interventional

Who can take part

  • Be a man age 40 to 65
  • Have had radical prostatectomy (prostate removal) for prostate cancer with no spread (no metastasis), and surgery was under 60 days ago
  • Your cancer must not be T3 or T4 stage, and you should not need other prostate cancer treatments like radiation or hormone therapy
  • Before surgery, you should have fairly good erections (IIEF score over 22 in domain A)
  • You must have stable heterosexual partner plans (together for more than 2 months and willing to stay together during the study)
  • You must take tadalafil 5 mg every day from day 30 to day 60 after surgery, and use at least 80% of the pills in that time window

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05955001Recruiting· Phase 2/Phase 3
Tadalafil for early urinary symptoms after prostate surgery

This trial studies whether daily tadalafil (5 mg) can improve early urinary trouble and erection function after endoscopic prostate tissue removal. It may help men whose urinary symptoms continued even after prior medicine.

Al Mansurah, Dakahlia Governorate
NCT07576335Recruiting· Phase 2
Prehabilitation and rehabilitation for prostate cancer surgery

This study tests a program that combines exercise, nutrition, and mental preparation before and after prostate removal surgery. The goal is to help you recover faster and keep better urinary and sexual function.

Sydney, New South Wales
NCT02706561Recruiting
Helping men stick with erectile rehab after prostate surgery

This study tests a program to help men follow sexual (erection) rehabilitation after prostate cancer surgery. It may help improve or maintain erectile functioning by supporting the right rehab steps in the months after surgery.

New York, New York
NCT06875258Recruiting· Phase 4
Penile rehab after nerve-sparing prostate surgery

This trial tests a penile rehabilitation program for men who have nerve-sparing prostate cancer surgery. It aims to help improve erections and sexual function after the procedure.

Nijmegen, Gelderland
NCT07863388Not yet recruiting
Platelet-rich plasma for erectile dysfunction after prostate removal

This study tests whether injections of platelet-rich plasma (a concentrate from your own blood) can improve erectile function in men who had erectile dysfunction after prostate removal surgery. Participants stop other erectile dysfunction treatments during the study to see if this treatment works on its own.

Herlev
NCT07707505Not yet recruiting
Exosomes or ozone therapy for erectile dysfunction after prostate surgery

This trial tests two new treatments for erectile dysfunction that occurred after robotic prostate surgery for prostate cancer. It compares a shot of exosomes (tiny particles that help healing) into the penis with rectal ozone therapy to see which works better.

Istanbul, Başakşehir

Hear when a new Erectile Dysfunction Following Radical Prostatectomy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.