Medication versus surgery for narrowed small intestine in Crohn's disease
Part of Digestive system clinical trials.
This study compares medical treatment with surgery for people with Crohn's disease who have a narrowing (stricture) in their small intestine that causes blockages. The goal is to see which approach is better at managing symptoms and preventing complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have Crohn's disease affecting the small intestine with a narrowing that causes symptoms like cramps or blockages.
- You have a score above 2 on a special test called the CREOLE score, which helps doctors decide how severe the narrowing is.
- You are not currently taking certain medications like steroids (above a low dose) or biologics within the last 8 weeks.
- You do not have other complications like fistulas, abscesses, or active disease in the colon.
- You are not pregnant or breastfeeding, and you do not have infections like HIV or hepatitis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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