Oral probiotic-and-prebiotic drink to prevent colon polyps returning
Part of Cancer, Digestive system clinical trials.
This study tests whether an oral synbiotic (a probiotic plus a prebiotic) can reduce the chance that advanced colon growths come back after they were removed. It also looks at changes in stool-related bacterial “gene markers” that may signal lower risk over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 90 years old.
- You recently had advanced colon growths removed, and a pathology lab confirmed they were removed (no leftover cancer or polyp that’s meant to be removed).
- Your colonoscopy before/around the procedure was considered high quality (complete exam of the whole colon and good bowel cleansing in each section).
- You must be able and willing to return for surveillance colonoscopies during the study.
- You cannot have certain conditions that raise risk or make treatment unsafe, such as inflammatory bowel disease, hereditary polyposis syndromes, or being immunocompromised (for example, on stronger immune-suppressing drugs or chemotherapy).
- You must not be pregnant or breastfeeding, and you must not have major severe health problems (an anesthesia risk score of 4 or higher).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking a probiotic called Clostridium Butyricum after colon polyp removal can lower the chance of polyps coming back. It is looking for people who had adenomas removed and are not already taking certain supplements or antibiotics.
This trial tests a Traditional Chinese Medicine herbal formula (Jianpi Lishi Jiedu Granules) to see if it can prevent colorectal advanced adenomas (a precancerous polyp) from coming back after they have been removed during a colonoscopy. It is recruiting people who have had such a polyp removed and whose body has a specific TCM pattern ('Spleen Deficiency and Dampness Toxin').
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
This trial tests whether Shenbai Granules, a traditional Chinese medicine, can prevent low-risk colon polyps from coming back after they have been removed. It is for people who have had certain types of colon polyps removed and have a specific pattern of spleen weakness with dampness and heat according to Chinese medicine.
This study aims to develop a tool using gut bacteria and metabolites to predict if high-risk colon polyps will come back after removal. If you are between 40 and 75 and have had certain types of colon polyps removed, you may be able to help us build better prediction methods.
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Hear when a new Colorectal Adenoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.