Clin2
NCT05592886Possibly a fitRecruiting

Oral probiotic-and-prebiotic drink to prevent colon polyps returning

Colorectal NeoplasmsColorectal AdenomaColorectal CancerAdvanced Adenoma

Part of Cancer, Digestive system clinical trials.

This study tests whether an oral synbiotic (a probiotic plus a prebiotic) can reduce the chance that advanced colon growths come back after they were removed. It also looks at changes in stool-related bacterial “gene markers” that may signal lower risk over time.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
649 people
Ages
18 years to 90 years
Study type
Interventional

Who can take part

  • You are 18 to 90 years old.
  • You recently had advanced colon growths removed, and a pathology lab confirmed they were removed (no leftover cancer or polyp that’s meant to be removed).
  • Your colonoscopy before/around the procedure was considered high quality (complete exam of the whole colon and good bowel cleansing in each section).
  • You must be able and willing to return for surveillance colonoscopies during the study.
  • You cannot have certain conditions that raise risk or make treatment unsafe, such as inflammatory bowel disease, hereditary polyposis syndromes, or being immunocompromised (for example, on stronger immune-suppressing drugs or chemotherapy).
  • You must not be pregnant or breastfeeding, and you must not have major severe health problems (an anesthesia risk score of 4 or higher).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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