Zoledronic acid in bone cement after tumor scraping
Part of Cancer clinical trials.
This trial tests whether adding zoledronic acid (a bone-strengthening medicine) into bone cement at the surgical site can help prevent giant cell bone tumor from coming back after surgeons scrape it out from inside the bone. It is for people whose tumor can be treated with a specific “scrape-and-reconstruct” surgery and who have not had related medicines before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a primary (first-time) giant cell tumor of bone.
- Your tumor can be treated with intralesional curettage (scraping out from inside) with enough intact bone left to reconstruct the area.
- You have not taken denosumab or bisphosphonate medicines before (including zoledronic acid).
- Your doctor expects you will live longer than 18 months.
- You are able and willing to sign the informed consent form and do follow-up check-ins after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether taking a bone-strengthening medicine called a bisphosphonate after surgery can lower the chance that a giant cell tumor in a leg or arm comes back. It may help prevent recurrence after removing the tumor from the bone.
This Phase 3 study tests narlumosbart (JMT103) to see if it works and is safe for people with giant cell tumor of bone that cannot be fully removed with surgery. If you qualify, you may be compared against another treatment and monitored closely for side effects and tumor response.
This trial tests if adding a bone-strengthening drug (bisphosphonate) to standard antibiotic treatment (vancomycin) works better for a certain type of long-term bone infection (osteomyelitis) that needs surgery. It may help people with a staph infection in their thigh or shin bone who are otherwise fairly healthy.
This real-world study looks at how the medicine zoledronic acid affects bone-related problems in people with breast cancer that has spread to the bone. It may help reduce events like fractures or other bone complications by protecting bone health.
This trial tests if a bone-strengthening drug called zoledronic acid can help people with congenital dyserythropoietic anemia (CDA), a rare type of anemia. It's for adults with moderate to severe anemia who may also need blood transfusions.
This trial tests if a bone-strengthening medicine called zoledronate can help prevent bone problems in children and teens who have had a stem cell transplant. It may be an option for patients with low bone density or those who develop graft-versus-host disease after transplant.
Hear when a new Giant Cell Tumor of Bone trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.