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NCT07375290Possibly a fitRecruiting

Zoledronate for Bone Health After Stem Cell Transplant

Hematopoietic Stem Cell Transplantation

Treatments studied

Part of Blood & lymphatic, Bones, joints & muscles clinical trials.

This trial tests if a bone-strengthening medicine called zoledronate can help prevent bone problems in children and teens who have had a stem cell transplant. It may be an option for patients with low bone density or those who develop graft-versus-host disease after transplant.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
20 people
Ages
5 years to 18 years
Study type
Interventional

Who can take part

  • You are between 5 and 18 years old.
  • You are getting a stem cell transplant and have low bone density, or you have already had a stem cell transplant and developed graft-versus-host disease (a complication from the donor cells).
  • You do not have Fanconi anemia or other conditions that increase cancer risk from radiation.
  • You have not taken bone-strengthening medicines like zoledronate or alendronate before.
  • Your vitamin D level is not very low (below 20 ng/mL).
  • You do not have active infections, kidney problems, or other bone diseases.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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