Pyridostigmine to help constipation in Parkinson’s
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult (18 or older) and able to sign consent
- Be able to swallow and take pills by mouth during the study
- Have Parkinson’s disease that meets specific diagnosis rules used in the UK
- Have functional constipation with three or fewer bowel movements per week
- If you can become pregnant or your partner is pregnant, you must use strict birth control during the study and for 28 days after the last dose
- Do not have certain health issues (including prior bowel surgery or bowel/bladder blockage), and do not have a known allergy to the study drug
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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