Surgery for severe late rectal damage from pelvic radiation
Part of Digestive system clinical trials.
This trial tests a surgical procedure (called PE-Bacon) for severe late damage to the rectum caused by previous pelvic radiation therapy. It aims to repair or remove the damaged tissue to relieve painful or life-disrupting symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have had radiation therapy to the pelvic area (for a cancer in the prostate, bladder, uterus, or similar) at least 6 months ago.
- You have a serious late complication from that radiation, such as a deep rectal ulcer, narrowing or blockage of the rectum, a rectal tear or hole, a fistula (an abnormal connection) between the rectum and vagina, severe anal pain, or rectal bleeding that hasn't improved after a stoma.
- Your original cancer is under control (no signs of recurrence or spread).
- You are healthy enough to have general anesthesia (being put to sleep for surgery).
- You have never had a stoma (a surgical opening in the belly to collect stool) before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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