Continuous nerve block for pain from multiple broken ribs

This study compares two types of nerve blocks (injections near the ribs) to see which works better for pain after multiple rib fractures. The goal is to find a less invasive option that relieves pain just as well as the standard method.

This trial tests whether freezing a specific nerve (a “cryoneurolysis” treatment) through a catheter can better control pain from traumatic rib fractures. It’s offered to adults who have rib fractures soon after hospital admission and can use a pain control method called patient-controlled regional analgesia.

This trial studies a numbing injection (called a serratus plane block) given near the ribs to help with breathing and pain after rib fractures. It aims to see if this injection improves your breathing pattern, which could help you recover more comfortably.

This trial tests a procedure called cryoablation that uses extreme cold to numb the nerves between the ribs, which may reduce pain and help you breathe easier after a rib fracture. It targets people with multiple rib fractures and significant pain but without certain other injuries.

This Phase 3 study tests whether low-dose dexmedetomidine (a calming/pain-related medicine used during anesthesia or ICU care) works better than normal saline to reduce hard-to-control rib fracture pain. It may help people with multiple broken ribs who still have significant pain despite other treatments.

This trial compares two medicines added to a numbing injection to improve pain relief for recent rib fractures. It measures how well each combination controls pain and aims to find the better option for patient comfort.