Studying why reflux reaches the throat and what stops it
Part of Digestive system clinical trials.
This study looks at the “upward reflux” that can irritate the throat and sometimes worsen symptoms like cough or asthma. It aims to understand the mechanisms that prevent or allow throat reflux, which may lead to better ways to manage symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old
- You have reflux disease symptoms (such as regurgitation) and possibly throat symptoms, or you have asthma (with or without throat symptoms)
- If you have reflux on long-term acid-suppressing medicine, you may qualify if your reflux symptom score is above 13
- If you have asthma, you must not be having a current flare-up (no recent worsening breathing symptoms)
- You must be able to give informed consent, and you cannot be pregnant
- You should not have certain allergies (lidocaine nasal anesthesia or green food dye) or active substance abuse
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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