Clin2
NCT05735483Possibly a fitEnrolling by invitation

Long-term lebrikizumab study for moderate to severe eczema

Atopic DermatitisEczema

Treatments studied

Part of Genetic & congenital, Immune system & allergy, Skin clinical trials.

This Phase 3 trial studies whether lebrikizumab is safe and continues to work over the long term for children and teens with moderate-to-severe atopic dermatitis (eczema). It’s meant for people who already finished a related earlier study and can safely continue.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
333 people
Ages
6 months to 18 years
Study type
Interventional

Who can take part

  • You must have participated in the earlier study (KGBI) and fully completed its treatments and last visit.
  • If you take part as someone who could become pregnant, you must use highly effective birth control during the study (following local study rules).
  • You must not have had a serious side effect during KGBI that doctors felt was related to lebrikizumab and made continuing too risky.
  • You must not have had a side effect during KGBI that doctors felt was related to lebrikizumab and caused stopping the study treatment.
  • You must not be pregnant, breastfeeding, or planning pregnancy or breastfeeding during the trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06807268Recruiting· Phase 3
A study of abrocitinib for children ages 6–11 with eczema

This trial tests a daily pill called Abrocitinib to see if it can help children ages 6 to 11 with moderate-to-severe eczema that hasn't gotten better with creams or ointments. Eczema (also called atopic dermatitis) causes itchy, red skin, and this medicine might calm the immune response to reduce itching and rashes.

Birmingham, Alabama
NCT06807281Recruiting· Phase 3
Abrocitinib for children with eczema: long-term study

This study tests the long-term safety and effectiveness of abrocitinib (Cibinqo) for children aged 6 to 12 with moderate to severe eczema that hasn't improved with creams. It may help their skin clear and reduce itching.

Birmingham, Alabama
NCT06947993Recruiting· Phase 2
Study of a new treatment for moderate to severe eczema

This study tests an experimental treatment for people with moderate to severe eczema that has lasted at least a year. It aims to see if the new medicine can help control symptoms better than current options.

Birmingham, Alabama
NCT06988605Recruiting
Nemolizumab for teens and adults with moderate-to-severe eczema

This study looks at how well nemolizumab works in everyday practice for people with moderate-to-severe atopic dermatitis (eczema). It helps researchers understand the real-world benefits and safety of this treatment.

Birmingham, Alabama
NCT05995964Recruiting· Phase 2
Study of two new medicines for eczema

This study tests two new study medicines (PF-07275315 and PF-07264660) for people with moderate to severe eczema that hasn't responded well to other treatments, including biologics. The goal is to see if these medicines can help reduce itching and clear the skin.

Birmingham, Alabama
NCT06906497Recruiting· Phase 4
Lebrikizumab for moderate-to-severe eczema

This trial tests an injectable drug called lebrikizumab for people with moderate-to-severe eczema (atopic dermatitis) that has not been well controlled with topical treatments. It may help reduce skin symptoms and itching.

Folsom, California

Hear when a new Atopic Dermatitis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.