Testing immune therapy put into the belly for cancer fluid
Treatments studied
Part of Cancer clinical trials.
This trial studies whether an immune-blocking drug placed directly into the belly cavity can help people with cancer-caused fluid buildup (malignant ascites) from stomach, pancreas, or bile-duct cancers. It may help shrink the fluid and slow the illness, but you must meet specific safety and treatment-history requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cancer fluid in the belly (malignant ascites) confirmed by a test of tissue or cells, from stomach, pancreatic, or bile-duct adenocarcinoma
- Your belly fluid is more than 1000 mL
- You have not had treatment placed into the belly for this fluid before (including belly-cavity procedures for treatment)
- You can likely live at least 4 weeks, and you can get blood counts checked showing platelets are at least 50,000
- You do not have an active infection or known bleeding disorder, and you don’t have serious heart/lung problems or recent heart disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests three drugs (bevacizumab, serplulimab, and rmhTNF-NC) given together to treat fluid buildup in the belly caused by digestive system cancers. It’s for people whose ascites has not improved after standard treatments.
This trial tests a new drug, SIM0388, for people whose cancer has spread and caused fluid buildup in the belly. It aims to see if the drug is safe and can help reduce the fluid.
This trial tests a pill called apatinib in people whose cancer has spread to the belly and causes fluid to build up (malignant ascites). Apatinib works by cutting off the blood supply that tumors need to grow, which may help reduce the fluid and ease symptoms.
This trial tests a drug called liposomal irinotecan, given alone or with other medications, to treat fluid buildup in the belly caused by digestive system cancers. It's for people who have already tried standard treatments without success.
This trial tests a drug called tocilizumab, which is given through the tube that drains fluid from your chest or belly. The goal is to see if it can help control cancer-related fluid buildup and improve symptoms.
This study tests an experimental drug called WSK-IM02 that is given directly into the chest or belly to treat fluid buildup caused by advanced cancer. It may help reduce symptoms like shortness of breath or belly swelling and improve quality of life.
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