Experimental drug for fluid buildup in people with advanced cancer
Part of Cancer, Lungs & breathing clinical trials.
This study tests an experimental drug called WSK-IM02 that is given directly into the chest or belly to treat fluid buildup caused by advanced cancer. It may help reduce symptoms like shortness of breath or belly swelling and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have an advanced solid tumor, and it has caused fluid to build up in your chest or belly (this is called a malignant effusion).
- You have already had standard cancer treatment, but the tumor spread and the fluid symptom appeared.
- You are well enough to be up and about (ECOG 0-2), or if you are less active, removing the fluid could make you feel better.
- Your organs are working well enough for this treatment.
- You are able to have a tube placed for drainage, or already have one in place.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug, SIM0388, for people whose cancer has spread and caused fluid buildup in the belly. It aims to see if the drug is safe and can help reduce the fluid.
This trial tests a drug called tocilizumab, which is given through the tube that drains fluid from your chest or belly. The goal is to see if it can help control cancer-related fluid buildup and improve symptoms.
This trial studies whether an immune-blocking drug placed directly into the belly cavity can help people with cancer-caused fluid buildup (malignant ascites) from stomach, pancreas, or bile-duct cancers. It may help shrink the fluid and slow the illness, but you must meet specific safety and treatment-history requirements.
This trial studies specific markers (biomarkers) found in fluid from a chest drain to better understand pleural effusions (fluid around the lungs), especially when fluid keeps coming back after treatment. You may be helped by contributing to research that could improve how these effusions are diagnosed and managed.
This trial tests three drugs (bevacizumab, serplulimab, and rmhTNF-NC) given together to treat fluid buildup in the belly caused by digestive system cancers. It’s for people whose ascites has not improved after standard treatments.
This early-phase trial tests an experimental drug called GK02 for people with advanced cancer who have fluid buildup in the belly (malignant ascites). The drug is given directly into the belly to try to reduce the fluid and control symptoms.
Hear when a new Malignant Ascites trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.