IVF trial using your own immune cells to support embryo transfer
Part of Women’s health & pregnancy clinical trials.
This trial studies whether placing your own immune cells (PBMCs) that have been adjusted with a medicine called IFN-<i>t</i> before embryo transfer can improve IVF success. It may help support the uterine environment around the time of implantation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently doing IVF/assisted reproduction and plan an embryo transfer
- You have primary infertility (difficulty getting pregnant when you have not previously had a pregnancy)
- You have regular menstrual cycles
- Your planned embryo transfer is only with euploid embryos (embryos with the usual number of chromosomes)
- You do not have uterine problems or active inflammation/infection in the uterine lining
- You do not have certain immune/thyroid/autoimmune antibodies or bleeding/clotting genetic issues, and you do not have cancer or HIV/hepatitis infections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study measures changes in your blood immune markers during frozen embryo transfer when the embryo is chromosomally normal. It may help clinics understand what blood immune patterns relate to successful pregnancy in natural or hormone-prepared cycles.
This trial tests whether infusing a special concentrate of your own platelets (platelet-rich plasma) into the uterus before embryo transfer can help women who have had failed transfers or a thin uterine lining. The goal is to improve the chances of a successful pregnancy.
This trial studies whether giving your own immune cells (PBMC) to the uterus, modified with interferon (IFN‑t), can improve how endometrial (uterine lining) cells behave during infertility treatment. It may help some people with primary infertility who are undergoing assisted reproduction.
This study gives a small amount of your own immune cells into the uterus to change the immune environment in the uterine lining. It aims to improve how the uterine lining supports implantation, especially for people trying to conceive with embryo transfer of normal (euploid) embryos.
This study looks at whether testing the immune cells in the uterus and then personalizing treatment improves the chance of success for patients who have a single embryo transfer. Eligible patients had the immune test and then a single blastocyst transfer within nine months.
This trial tests whether injecting a woman's own cells into her ovaries can help improve egg production for women with very low ovarian reserve. It is for women under 45 who have had poor results from IVF in the past.
Hear when a new Infertility, Female trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.