Detox medicine study for primary sclerosing cholangitis
Treatments studied
Part of Digestive system clinical trials.
This Phase 2 trial studies a “detoxification” approach to improve liver and bile-duct function in people with primary sclerosing cholangitis (PSC). It may help lower abnormal bile flow markers and see whether the treatment is safe for your liver.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with PSC for at least 6 months based on a bile-duct scan (ERCP or MRCP).
- Your blood test shows alkaline phosphatase (ALP) is more than 1.5 times the lab’s upper normal limit.
- You are either taking ursodeoxycholic acid (UDCA) at a stable dose for over 6 months, or stopped it at least 4 weeks ago.
- You do NOT have signs of advanced/unstable liver function (for example, bleeding from stomach veins, fluid buildup in the belly, or confusion from liver disease).
- You should not need a liver transplant within the next year (based on a risk score), and your lab values must meet study thresholds.
- You must not have certain other liver conditions, active infections, or recent severe bile-duct infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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