Ketamine medicine trial for chronic nerve pain in adults
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This Phase 1/2 study tests hydroxynorketamine (a related ketamine-type medicine) to see if it can reduce chronic nerve pain in the arms or legs. You may be able to join if you have nerve pain for more than 3 months and meet safety and health check requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult age 18 to 75 and have nerve pain in the arms or legs for more than 3 months
- Score at least 4 on the DN4 questionnaire, which checks for nerve pain symptoms
- Be able to read and write English enough to complete study paperwork and visits
- Have a body mass index (BMI) between 18 and 35, and weight between 50 and 120 kg (110–264 lb)
- Have safe heart and electrical test results: blood pressure in a supine position for 5 minutes, and an ECG with QTc 450 ms or less
- Be willing to follow study rules on medicines, alcohol/caffeine/tobacco/nicotine, diet before dosing, and consent to participate
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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