Chidamide plus venetoclax for hard-to-treat APL
Part of Blood & lymphatic, Cancer clinical trials.
This trial studies chidamide and venetoclax in people with a specific type of acute promyelocytic leukemia (APL) that has not responded to standard treatment with all-trans retinoic acid (RA) plus arsenic. It may help by testing a new combination for cases in “non-remission” status.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have PML-RARα positive APL (a specific leukemia marker).
- Your leukemia is not in remission after RA plus arsenic treatment.
- Your expected lifespan is at least 3 months (and not under 2 months).
- You are able to give informed consent to join the study.
- You do not currently have an uncontrolled infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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