Hematology
Blood & lymphatic clinical trials
Anemia, clotting disorders, and other conditions of the blood and lymphatic system. We’re tracking 4,915 recruiting studies in this area right now.
By phase
- Not applicable2,021
- Phase 21,071
- Phase 1792
- Phase 1/Phase 2476
- Phase 3346
- Phase 4126
- Phase 2/Phase 383
Top conditions
- Multiple Myeloma327
- Acute Myeloid Leukemia281
- Lymphoma178
- Sickle Cell Disease133
- Myelodysplastic Syndromes128
- Acute Lymphoblastic Leukemia118
- Leukemia100
- Chronic Lymphocytic Leukemia96
- Follicular Lymphoma70
- Hematologic Malignancy67
- Myelodysplastic Syndrome64
- Hodgkin Lymphoma63
- Mantle Cell Lymphoma62
- Anemia56
- Diffuse Large B Cell Lymphoma54
- Malignant Solid Neoplasm53
- Acute Myeloid Leukemia (AML)48
- Lymphedema48
Leading sponsors
- M.D. Anderson Cancer Center145
- Institute of Hematology & Blood Diseases Hospital, China138
- National Cancer Institute (NCI)96
- The First Affiliated Hospital of Soochow University67
- Memorial Sloan Kettering Cancer Center63
- City of Hope Medical Center58
- Mayo Clinic55
- Assistance Publique - Hôpitaux de Paris45
- St. Jude Children's Research Hospital44
- Peking University People's Hospital42
Where studies are running
- California395
- Texas185
- Alabama156
- Maryland151
- Arizona125
- Florida105
- Massachusetts103
- New York98
- Ohio70
- Minnesota69
Recruiting studies4,915 total
- NCT06430736RecruitingPhase 2
Tocilizumab before or during CAR-T therapy
This study tests whether giving tocilizumab (a drug that calms inflammation) before CAR-T cell therapy helps prevent side effects. It compares using it ahead of time versus only when needed. You may be eligible if you are scheduled for CAR-T therapy for lymphoma, leukemia, or myeloma.
Bern, Canton of BernAges 18 years+ - NCT06163430RecruitingPhase 1/Phase 2
Study of MK-4208 for chronic myeloid leukemia
This trial tests a new pill that may help people with chronic myeloid leukemia (CML) when other treatments have stopped working or caused side effects. It might offer another option for controlling the disease.
Birmingham, AlabamaAges 18 years+ - NCT07875478Recruiting
Tracking factor X deficiency to improve patient care
This study collects health information and blood samples from people with factor X deficiency (a rare bleeding disorder) and their close family members. The goal is to learn more about how the condition progresses over time, which could lead to better treatment and management.
FlorenceAges Any age - NCT07200102RecruitingPhase 1
Selinexor after CAR-T for high-risk multiple myeloma
This study tests whether taking selinexor after CAR-T cell therapy can help keep multiple myeloma from coming back. It is for people whose myeloma is high-risk or still has signs of disease after CAR-T.
St Louis, MissouriAges 18 years+ - NCT06941870RecruitingPhase 4
Prevention treatment for hemophilia A with joint swelling
This study tests a preventive treatment called efanesoctocog alfa to see if it can help people with moderate to severe hemophilia A who have joint swelling (synovial hypertrophy). It aims to reduce joint bleeding and improve joint health.
Los Angeles, CaliforniaAges 12 years+ - NCT05986240RecruitingPhase 1
Danvatirsen plus venetoclax for advanced blood cancers
This trial tests a new drug called danvatirsen, first alone and then with venetoclax, for people with advanced acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) that have not responded to standard treatments. The goal is to see if this combination can help shrink or control the cancer.
The Bronx, New YorkAges 18 years+ - NCT07109219RecruitingPhase 1/Phase 2
Study of AZD4512 alone or with other drugs for leukemia
This study tests a new medicine called AZD4512, given alone or with other cancer drugs, for people whose B-cell acute lymphoblastic leukemia (a type of blood cancer) has come back or not improved after treatment. The goal is to see if it can help control the disease.
Duarte, CaliforniaAges 12 years+ - NCT05735704Recruiting
Blood cancer early detection study
This study looks for early signs of blood cancers in people who have them or are at higher risk, like family members or older adults. It aims to find cancer sooner, which may lead to better outcomes.
OlomoucAges 18 years+ - NCT06691217RecruitingPhase 2
Study of a new drug to reduce blood vessel swelling in TET2 mutations
This study tests an investigational drug that may reduce swelling (inflammation) inside the blood vessels of people with heart disease and a specific gene change called TET2. This gene change is linked to higher inflammation and heart risks, and the drug aims to lower that risk.
Boston, MassachusettsAges 18 years+ - NCT00736749Recruiting
Long-term health check for childhood cancer survivors
This trial tracks the long-term health of people who took part in previous Children's Oncology Group studies. It helps doctors understand the lasting effects of cancer treatment and improve care for survivors.
Birmingham, AlabamaAges Any age - NCT07387926RecruitingPhase 1/Phase 2
Testing asciminib for children and young adults with a type of leukemia
This trial tests an experimental drug called asciminib for children and young adults whose leukemia (a specific type of B-cell acute lymphoblastic leukemia with certain gene changes) has come back or not responded to treatment. The goal is to see if the drug is safe and effective for these patients.
Sydney, New South WalesAges 1–30 - NCT07731789RecruitingPhase 2
Antibody combo for newly diagnosed follicular lymphoma
This trial tests two antibody medications, tafasitamab and rituximab, as the first treatment for newly diagnosed follicular lymphoma. The goal is to see if this combination can effectively control the lymphoma and potentially reduce the need for more intensive therapies.
Seattle, WashingtonAges 18 years+ - NCT06985212Recruiting
Study of acid sphingomyelinase deficiency in children and adults
This study follows people with acid sphingomyelinase deficiency (ASMD) over time to learn more about how the condition changes. You won't get any new treatment, but your participation will help doctors better understand ASMD.
Paris, FranceAges 2 years+ - NCT07557056RecruitingPhase 2
Oral combination treatment for untreated chronic lymphocytic leukemia
This clinical trial tests two oral medications, nemtabrutinib and venetoclax, given together to people with untreated CLL or SLL. The goal is to see if this combination effectively kills cancer cells and helps you stay in remission with manageable side effects.
Columbus, OhioAges 18 years+ - NCT05633615RecruitingPhase 2
Testing new drug options after CAR T for aggressive lymphoma
This Phase 2 study tests whether adding or switching drug treatments after CAR T-cell therapy can improve outcomes for people with certain aggressive lymphomas that have come back or did not respond. It mainly looks at who remains disease-stable/partly improved after CAR T and what treatment approach works best next.
Tucson, ArizonaAges 18 years+ - NCT06703606RecruitingPhase 1
Switching from Emicizumab to Marstacimab for Severe Hemophilia A
This study tests if switching from emicizumab to a new medicine called marstacimab is safe and effective for people with severe hemophilia A. You must have been on emicizumab for at least 6 months and not have a history of blood clots or heart disease.
La Jolla, CaliforniaAges 12–74 - NCT06303193RecruitingPhase 1/Phase 2
Testing a kinase inhibitor drug for MDS and MDS/MPN in adults and teens
This trial tests a drug called pacritinib in people with myelodysplastic syndromes (MDS) or MDS/myeloproliferative neoplasms (MDS/MPN). The drug targets several proteins that may help control the disease, especially for those who have not responded to other treatments.
Bethesda, MarylandAges 12–120 - NCT06904066RecruitingPhase 1
Personalized T cell therapy for blood cancers
This trial tests a treatment that takes your own immune cells, modifies them to attack cancer cells, and gives them back to you. It is for people with certain blood cancers who have specific gene changes.
Bethesda, MarylandAges 18–120 - NCT07683104Recruiting
How trisomy 8 autoinflammatory disease progresses over time
This study follows people who have trisomy 8 (an extra copy of a chromosome) that causes inflammation and mouth/genital ulcers, and their family members. Researchers want to learn how this condition changes over time, so they can better understand and treat it.
Bethesda, MarylandAges 1 day–99 years - NCT06869499Recruiting
Screening for a rare enzyme disease in patients with lung scarring
This study checks if people with certain lung changes (called interstitial lung disease) might have a rare enzyme deficiency that can cause lung and other organ problems. Finding this could lead to better treatment options.
ParisAges 15–60 - NCT07772596Recruiting
Chatbot for young adult cancer survivors
This study tests a chatbot that offers support and advice for cancer survivors. If you're a young adult dealing with symptoms or side effects, this could help you manage them better.
Ann Arbor, MichiganAges 18–39 - NCT07572136RecruitingPhase 1
CAR T-cell therapy for hard-to-treat B-cell leukemia
This trial tests a new type of CAR T-cell therapy—a treatment that uses your own immune cells engineered to fight leukemia cells. It is designed for patients with B-cell acute lymphoblastic leukemia (ALL) that has come back or stopped responding to standard treatments, and whose leukemia cells have a specific marker called TSLPR.
Bethesda, MarylandAges 18–120 - NCT07617428Enrolling by invitation
Testing a new blood loss monitor during surgery
This study tests a new system designed to accurately measure blood loss during elective surgery. If you're having planned urological or general surgery, this trial may help doctors better monitor your blood during the procedure.
Lanzhou, GansuAges 18 years+ - NCT07357727RecruitingPhase 3
Study of Pelabresib and Ruxolitinib for Myelofibrosis
This trial tests a combination of two drugs (pelabresib and ruxolitinib) for people with myelofibrosis whose spleen is enlarged and who have bothersome symptoms. It aims to see if adding pelabresib to standard care helps control the disease better.
New Haven, ConnecticutAges 18 years+
Common questions
- How many blood & lymphatic clinical trials are recruiting?
- Clin2 is tracking 4,915 recruiting hematology studies from the U.S. registry right now, out of 7,233 we cover in this area in total.
- What does “Blood & lymphatic” cover here?
- Anemia, clotting disorders, and other conditions of the blood and lymphatic system. We group each study into blood & lymphatic based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a blood & lymphatic trial near me?
- Use the search to filter blood & lymphatic studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.