Clin2
NCT05901571Possibly a fitNot yet recruiting

Acupuncture and escitalopram for major depression

Depressive Disorder, Major

Treatments studied

Part of Mental health clinical trials.

This study tests whether adding acupuncture to a common antidepressant (escitalopram) helps improve depression symptoms more than the medication alone. It aims to see if this combination can be a safe and effective treatment for adults with major depression.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
216 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with major depressive disorder (a type of depression) according to standard psychiatric criteria.
  • You score at least 17 on the Hamilton Depression Rating Scale (a questionnaire that measures depression severity).
  • You can read and understand Mandarin Chinese, have at least 9 years of education, and are willing to follow the study rules.
  • You have not received acupuncture treatment in the past year.
  • You are not currently taking antidepressants, and you have never failed treatment with escitalopram (the study drug).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07552246Recruiting· Phase 4
Acupuncture vs medication for depression and anxiety

This study compares acupuncture with standard medication for reducing depression, anxiety, and related sleep problems. It aims to see if acupuncture is a helpful alternative for people in China who are struggling with these conditions.

Kunshan, Jiangsu
NCT07003763Recruiting
Electroacupuncture for depression in cancer patients

This trial tests whether electroacupuncture can help treat depression caused by cancer or its treatments. It may be a safe option for people who have not tried acupuncture before and are not currently receiving active cancer treatments.

Shanghai
NCT05480150Recruiting
Study of brain and mood in people with depression or bipolar disorder

This study is following and assessing people with major depression or bipolar disorder to better understand the condition and how the brain relates to symptoms. It may help researchers develop more targeted support by comparing brain and health information over time.

Hangzhou, Zhejiang
NCT06828887Recruiting· Phase 2
Testing LV232 capsules for major depression

This trial tests a new medicine called LV232 for people with moderate to severe depression. Researchers want to find the best dose and check if it works safely.

Shanghai
NCT07611487Not yet recruiting
MRI study of acupuncture for moderate depression

This study uses brain scans (MRI) to see how acupuncture may quickly improve depression symptoms. If you are currently being treated for depression with moderate symptoms, you may join and help researchers learn if acupuncture could be a helpful option.

NCT07390981Not yet recruiting
Acupuncture to help safely reduce antidepressant dose

This study tests whether adding intradermal acupuncture (tiny needles placed just under the skin) can help people with depression safely reduce their antidepressant medication without symptoms coming back. It may offer a supportive way to taper off medication under medical supervision.

Hear when a new Depressive Disorder, Major trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.