Clin2
NCT05928429Possibly a fitRecruiting

Cold treatment to prevent nerve pain from weekly paclitaxel

CIPN - Chemotherapy-Induced Peripheral NeuropathyBreast Cancer

Part of Cancer, Skin clinical trials.

This trial tests whether cryotherapy (cooling the hands/feet during chemo) can prevent or lessen nerve pain caused by paclitaxel in people with early breast cancer. It may help you stay more comfortable and function better during treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
300 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have early-stage breast cancer and are scheduled to receive weekly paclitaxel (a chemotherapy drug) for 9 or 12 doses.
  • You are planned to receive paclitaxel 80 mg/m² over about 1 hour, once per week.
  • Your general ability to do daily activities is good (performance status 0–1).
  • You do not already have nerve damage in the arms or legs (sensory or motor neuropathy).
  • You do not have moderate or severe nerve pain symptoms or swelling in a limb (grade 2 or higher).
  • You do not have Raynaud’s symptoms or poor blood flow to the arms/legs (peripheral arterial ischemia).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07780955Recruiting
Cold therapy for nerve damage from paclitaxel chemotherapy

This study tests whether wearing cold gloves and socks during paclitaxel chemotherapy can prevent or reduce nerve damage in the hands and feet, a common side effect. If you are getting weekly paclitaxel for breast cancer, this might help keep your hands and feet more comfortable.

Bolzano, Bolzano
NCT07064798Recruiting
Cooling gloves and socks for nerve pain from chemo

This trial tests if wearing special cooling gloves and socks during chemotherapy can help prevent nerve damage, tingling, or numbness in your hands and feet. It is for people with breast or gynecologic cancer who are starting certain types of chemo that can cause these side effects.

Boston, Massachusetts
NCT07504770Not yet recruiting
Surgical glove compression to prevent nerve damage from paclitaxel

This trial tests whether wearing surgical gloves during paclitaxel chemotherapy can reduce nerve damage (neuropathy) in the hands. If it works, patients may experience less tingling, numbness, or pain in their hands.

Konya, Meram
NCT06422949Not yet recruiting
Cooling device to prevent nerve damage from breast cancer chemotherapy

This trial tests a cooling device (HILOTERM) that may help prevent nerve damage (peripheral neuropathy) in women with breast cancer receiving the chemotherapy drug paclitaxel. The device is used during treatment to keep the hands and feet cool, which might reduce tingling and numbness.

Milan
NCT07834281Not yet recruiting· Phase 4
Capsaicin patch to prevent nerve pain from paclitaxel

This study tests a high-strength capsaicin (chili pepper extract) patch placed on the hands and feet to try to prevent nerve damage caused by the chemotherapy drug paclitaxel. If it works, it could reduce painful tingling or numbness during treatment.

Cleveland, Ohio
NCT07377279Recruiting
Acupuncture and compression to prevent nerve pain from chemo

This trial tests whether acupuncture and compression therapy can prevent nerve damage caused by taxane chemotherapy in early-stage breast cancer. It aims to reduce numbness, tingling, or pain in the hands and feet.

Guangzhou, Guangdong

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.