Clin2
NCT05928429Possibly a fitRecruiting

Cold treatment to prevent nerve pain from weekly paclitaxel

CIPN - Chemotherapy-Induced Peripheral NeuropathyBreast Cancer

Part of Cancer, Skin clinical trials.

This trial tests whether cryotherapy (cooling the hands/feet during chemo) can prevent or lessen nerve pain caused by paclitaxel in people with early breast cancer. It may help you stay more comfortable and function better during treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
300 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have early-stage breast cancer and are scheduled to receive weekly paclitaxel (a chemotherapy drug) for 9 or 12 doses.
  • You are planned to receive paclitaxel 80 mg/m² over about 1 hour, once per week.
  • Your general ability to do daily activities is good (performance status 0–1).
  • You do not already have nerve damage in the arms or legs (sensory or motor neuropathy).
  • You do not have moderate or severe nerve pain symptoms or swelling in a limb (grade 2 or higher).
  • You do not have Raynaud’s symptoms or poor blood flow to the arms/legs (peripheral arterial ischemia).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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