Cooling device to prevent nerve damage from breast cancer chemotherapy
Part of Brain & nervous system, Cancer, Skin clinical trials.
This trial tests a cooling device (HILOTERM) that may help prevent nerve damage (peripheral neuropathy) in women with breast cancer receiving the chemotherapy drug paclitaxel. The device is used during treatment to keep the hands and feet cool, which might reduce tingling and numbness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman over 18 years old.
- You have been diagnosed with early-stage breast cancer that can be surgically removed (no spread to distant organs).
- Your doctor plans to give you weekly paclitaxel (a chemotherapy drug) for 12 weeks, possibly after other chemo drugs or with a targeted therapy called trastuzumab.
- You are generally in good health and able to handle daily activities (ECOG score 0-1).
- If you can become pregnant, you must have a negative pregnancy test before starting.
- You have no history of nerve damage, diabetes, cold- or blood-flow-related conditions, or other serious medical issues that could interfere.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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