Clin2
NCT05934669Possibly a fitRecruiting

Numbing medicines compared for small stitches in young children

Laceration of SkinAnxietyDischarge Time

Treatments studied

Part of Mental health clinical trials.

This trial tests three medicines given through the nose to keep children comfortable during minor procedures in the emergency department, specifically for closing small cuts with stitches. It may help find which nasal medicine works best and is safest for quick, minimal procedures.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
90 people
Ages
1 year to 5 years
Study type
Interventional

Who can take part

  • Child is between 1 and 5 years old
  • This ED visit is for stitches (suture repair) for a cut 5 cm or smaller
  • A parent or caregiver can speak English
  • Child does not have a known allergy or bad reaction to midazolam, dexmedetomidine, ketamine, or other sedatives
  • Child has normal vital signs for their age (especially heart rate and blood pressure)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05383495Recruiting· Phase 3
Calming medicine during child laceration repair

This trial tests a calming/anxiety-reducing medicine to see if it helps children feel less scared during stitches for a skin cut. It may help make the repair process easier for children and their caregivers.

London, Ontario
NCT07565116Recruiting
Numbing Nose Spray vs. Calming Liquid Before Pediatric Surgery

This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.

Diyarbakır, Outside of the US
NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery

This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.

Ljubljana
NCT07180095Not yet recruiting· Phase 1/Phase 2
Nasal sedation for young children before surgery

This study compares two sedative medicines given as a nasal spray to help children relax and reduce separation anxiety before surgery. It aims to find which medicine works better for children aged 2 to 6.

NCT06896721Not yet recruiting· Phase 4
Nasal calming medicine for children before surgery

This trial tests a medicine given as nose drops to help children relax before anesthesia and reduce confusion or agitation after surgery. It may make the anesthesia experience smoother for young children having minor surgeries.

NCT04195256Recruiting· Phase 2/Phase 3
Nasal sedation medicine for kids needing a quick procedure

This trial tests whether a nose spray (dexmedetomidine plus ketamine) can safely and effectively sedate children during an ED procedure for certain arm injuries. It may help reduce distress and improve comfort compared with usual care.

Edmonton, Alberta

Hear when a new Laceration of Skin trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.