Baclofen to help taper benzodiazepines more safely
Treatments studied
Part of Mental health clinical trials.
This trial tests whether baclofen can make it easier to reduce (taper) benzodiazepines in people who have been dependent for a long time and previously had trouble stopping. If you can safely take part, it may help improve the tapering process and reduce withdrawal problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have benzodiazepine dependence for more than 12 weeks.
- In the last 28 days, your average daily benzodiazepine dose was equivalent to 30–200 mg of diazepam.
- You previously tried a taper but were unable to fully stop at the planned pace.
- You must be able to give informed written consent and follow study pregnancy rules (if applicable).
- You must not have certain health or psychiatric conditions (like liver cirrhosis or schizophrenia/bipolar) and must avoid certain interacting medicines.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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