Study why repeated pregnancy problems happen in some cases
Treatments studied
Part of Genetic & congenital, Women’s health & pregnancy clinical trials.
This study looks at how the immune system may contribute to ongoing placenta inflammation in certain pregnancy histories. It may help researchers better understand causes behind pregnancy loss and related placental complications, using past placenta/tissue samples.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Both parents are adults (age 18 or older)
- You consent for the study and for the use of past samples (placenta/fetal DNA) or a child’s participation
- The mother’s pregnancy history matches one of these groups: chronic histiocytic intervillositis (CHI), anti-phospholipid syndrome (APS), or a normal consecutive term pregnancy
- For the mother in the CHI group: CHI was confirmed by placenta pathology with CD68 staining
- For the APS group: you have anti-phospholipid syndrome and a history of miscarriage(s)
- For the normal-pregnancy group: this is your third consecutive normal pregnancy ending at term (≥36 weeks) with a healthy baby
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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