Clin2
NCT05959603Possibly a fitRecruiting

Vancomycin powder during spinal surgery to prevent infection

Infection

Treatments studied

Part of Infections clinical trials.

This Phase 3 trial tests whether placing vancomycin powder in the wound during spinal fusion surgery can lower the chance of a surgical site infection. You might qualify if you’re having a specific type of spinal surgery and meet safety criteria.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
363 people
Ages
18 years to 90 years
Study type
Interventional

Who can take part

  • You are scheduled for a posterior spinal fusion surgery at the neurosurgery department
  • You (or your legal guardian) can understand and sign the consent form
  • You do not have an active infection that is being treated before surgery
  • You are not currently taking antibiotics for an infection other than the planned surgery
  • You are not allergic to vancomycin or cefazolin
  • Your kidney function is not severely reduced (stage 4 CKD with very low GFR 15–30 ml/min or worse)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04825522Recruiting· Phase 4
Vancomycin powder during spine surgery to prevent infection

This trial studies whether placing antibiotic powder (vancomycin) directly in the surgical wound during spine surgery can lower the chance of infection. It may help patients by reducing wound infections after surgery, but it also depends on your surgery details and follow-up timeline.

Windsor, Ontario
NCT03883022Recruiting
Vancomycin powder plus bone graft to prevent spine surgery infection

This trial tests whether placing vancomycin powder and your own bone graft during spine fusion surgery can lower the chance of infection after surgery. It’s meant for people having instrumented spine fusion after other treatments haven’t helped.

Taipei
NCT06504992Not yet recruiting· Phase 4
Vancomycin powder in surgery for open fractures

This study tests whether putting vancomycin antibiotic powder directly into the wound during surgery helps prevent infections in open fractures. If you are having surgery to fix an open fracture, this could reduce your risk of getting a bone infection.

Winnipeg, Manitoba
NCT06748144Not yet recruiting· Phase 2/Phase 3
Bone surgery antibiotic study

This study tests whether giving antibiotics directly into the bone during spinal fusion surgery helps prevent infections better than standard care. It may help you if you are having this specific type of back surgery.

Houston, Texas
NCT04993027Not yet recruiting· Phase 2
Vancomycin powder during hip or knee replacement to prevent infection

This study tests whether putting vancomycin powder in the surgical wound during hip or knee replacement surgery reduces the risk of infection. It is for adults having their first replacement due to osteoarthritis.

NCT07201987Not yet recruiting· Phase 2
Antibiotic and pain-relief beads for spinal fusion surgery

This trial tests placing antibiotic and pain-relieving beads directly into the spine during lower back fusion surgery. It aims to reduce infections and improve pain control after the operation.

Hear when a new Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.