Testing local removal versus radical surgery for rectal cancer
Part of Cancer, Digestive system clinical trials.
This trial looks at whether removing the rectal tumor locally (through the anus) can work as well as a more extensive operation after scans show no remaining cancer. It may help some people avoid bigger surgery if the cancer truly appears gone after treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have rectal adenocarcinoma and finished chemoradiation (nCRT)
- Your scans and exam suggest no remaining cancer (clinically complete remission)
- Blood tumor marker test (ctDNA) must show no remaining cancer
- Your tumor is in a spot reachable by a transanal local procedure, usually within about 6 cm above the anus
- You are between 18 and 75 years old, and your overall health is in ASA class I to III
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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